Endocrine Abstracts

Introduction: Osteoporosis in males is an underdiagnosed condition. It is considered to be of secondary pathogenesis in up to 60% of cases. In order to establish rational flow charts for the diagnosis and management of osteoporosis in men solid data seem to be necessary about the incidence of certain underlying diseases.Methods: In a prospective screening for hormonal alterations we analysed 65 patients with male osteoporosis according to laboratory para...

The German Acrostudy is at present the largest database on acromegalics (n=184) treated with pegvisomant (Somavert®). 91% pts underwent pituitary surgery, 45% received radiation therapy, and previous medical therapy included dopamine agonists (56%), octreotide (90%) and/or lanreotide (10%). Common concomitant diseases at baseline were hypertension (47.0%), diabetes mellitus (31.7%), and gallstone disease (25.6%). Efficacy analysis was performed in 134 pt...

QoL is an important outcome criterion in clinical research and is used to monitor treatment effects. Patients who have sustained SAH oftentimes have impaired QoL as do patients with untreated hypopituitarism. Considering the high degree of partial hypopituitarism in SAH survivors, we sought to elucidate the impact of neuroendocrine dysfunction on QoL and the prevalence of psychiatric sequelae in these patients.QoL, depression and symptoms of posttraumati...